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Allosteric Inhibition of Factor XIa. Sulfated Non-Saccharide Glycosaminoglycan Mimetics as Promising Anticoagulants

Recent development of sulfated non-saccharide glycosaminoglycan mimetics, especially sulfated pentagalloyl glucopyranoside (SPGG), as potent inhibitors of factor XIa (FXIa) (J. Med. Chem. 2013; 56:867–878 and J. Med. Chem. 2014; 57:4805–4818) has led to a strong possibility of developing a new line...

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Bibliografiske detaljer
Udgivet i:Thromb Res
Main Authors: Al-Horani, Rami A., Gailani, David, Desai, Umesh R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4526391/
https://ncbi.nlm.nih.gov/pubmed/25935648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2015.04.017
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