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Allosteric Inhibition of Factor XIa. Sulfated Non-Saccharide Glycosaminoglycan Mimetics as Promising Anticoagulants
Recent development of sulfated non-saccharide glycosaminoglycan mimetics, especially sulfated pentagalloyl glucopyranoside (SPGG), as potent inhibitors of factor XIa (FXIa) (J. Med. Chem. 2013; 56:867–878 and J. Med. Chem. 2014; 57:4805–4818) has led to a strong possibility of developing a new line...
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| Veröffentlicht in: | Thromb Res |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4526391/ https://ncbi.nlm.nih.gov/pubmed/25935648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2015.04.017 |
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