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Targeting the anionic region of human protease activated receptor 4 (PAR4) inhibits platelet aggregation and thrombosis without interfering with hemostasis

BACKGROUND: Human platelet activation and aggregation is a complex process. To date, many therapies have been developed targeting proteins that mediate this process to prevent unwanted activation. However, the current standard of care for acute coronary syndromes still has limitations including blee...

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Hlavní autoři: Mumaw, M. M., de la Fuente, M., Noble, D. N., Nieman, M.T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127092/
https://ncbi.nlm.nih.gov/pubmed/24888424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12619
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