Development and Characterization of Monoclonal Antibodies Against Protease Activated Receptor 4 (PAR4)

BACKGROUND: Protease activated receptor 4 (PAR4) is a G protein coupled receptor (GPCR) which is activated by proteolytic cleavage of its N-terminal exodomain. This generates a tethered ligand that activates the receptor and triggers downstream signaling events. With the current focus in the develop...

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Bibliografische gegevens
Gepubliceerd in:Thromb Res
Hoofdauteurs: Mumaw, Michele M., de la Fuente, Maria, Arachiche, Amal, Wahl, James K., Nieman, Marvin T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437850/
https://ncbi.nlm.nih.gov/pubmed/25890453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2015.03.027
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