Regio-selective Chemical-Enzymatic Synthesis of Pyrimidine Nucleotides Facilitates RNA Structure and Dynamics Studies

Isotope labeling revolutionized NMR studies of small nucleic acids, but to extend this technology to larger RNAs requires site-specific labeling tools to expedite NMR structural and dynamics studies. Using enzymes from the pentose phosphate pathway, we couple chemically synthesized uracil nucleobase...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Alvarado, Luigi J., LeBlanc, Regan M., Longhini, Andrew P., Keane, Sarah C., Jain, Niyati, Yildiz, Zehra F., Tolbert, Blanton S., D'Souza, Victoria M., Summers, Michael F., Kreutz, Christoph, Dayie, T. Kwaku
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127085/
https://ncbi.nlm.nih.gov/pubmed/24954297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402130
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge