Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation

Although oxidative tissue injury often accompanies viral infection, there is little understanding of how it influences virus replication. We show that multiple hepatitis C virus (HCV) genotypes are exquisitely sensitive to oxidative membrane damage, a property distinguishing them from other pathogen...

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Detalhes bibliográficos
Main Authors: Yamane, Daisuke, McGivern, David R., Wauthier, Eliane, Yi, MinKyung, Madden, Victoria J., Welsch, Christoph, Antes, Iris, Wen, Yahong, Chugh, Pauline E., McGee, Charles E., Widman, Douglas G., Misumi, Ichiro, Bandyopadhyay, Sibali, Kim, Seungtaek, Shimakami, Tetsuro, Oikawa, Tsunekazu, Whitmire, Jason K., Heise, Mark T., Dittmer, Dirk P., Kao, C. Cheng, Pitson, Stuart M, Merrill, Alfred H., Reid, Lola M., Lemon, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126843/
https://ncbi.nlm.nih.gov/pubmed/25064127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3610
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