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Comparison of Pre-Analytical FFPE Sample Preparation Methods and Their Impact on Massively Parallel Sequencing in Routine Diagnostics

Over the last years, massively parallel sequencing has rapidly evolved and has now transitioned into molecular pathology routine laboratories. It is an attractive platform for analysing multiple genes at the same time with very little input material. Therefore, the need for high quality DNA obtained...

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Dettagli Bibliografici
Autori principali: Heydt, Carina, Fassunke, Jana, Künstlinger, Helen, Ihle, Michaela Angelika, König, Katharina, Heukamp, Lukas Carl, Schildhaus, Hans-Ulrich, Odenthal, Margarete, Büttner, Reinhard, Merkelbach-Bruse, Sabine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126727/
https://ncbi.nlm.nih.gov/pubmed/25105902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104566
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