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Efficient Synthesis of THP/THF-Containing Macrolides via Palladium-Catalyzed Alkoxycarbonylative Macrolactonizations
A novel Pd-catalyzed cascade alkoxycarbonylative macrolactonization to construct THP/THF-containing bridged macrolactones in one step from alkendiols is described. Products with various ring sizes and substituents were obtained. Challenging macrolactones involving tertiary alcohols were synthesized...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126560/ https://ncbi.nlm.nih.gov/pubmed/24825410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201403006 |
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