Synthesis of Nitriles via Palladium-Catalyzed Water Shuffling from Amides to Acetonitrile

Palladium-catalyzed synthesis of nitriles from amides has been described. Two similar, but complementary reaction conditions have been identified to convert various amides including α,β,γ,δ-unsaturated amides, cinnamides, aromatic amides and alkyl amides to the corresponding nitriles in good to exce...

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Bibliographic Details
Main Authors: Zhang, Wandi, Haskins, Christopher W., Yang, Yang, Dai, Mingji
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213294/
https://ncbi.nlm.nih.gov/pubmed/25316145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01825g
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