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Efficient Synthesis of THP/THF-Containing Macrolides via Palladium-Catalyzed Alkoxycarbonylative Macrolactonizations

A novel Pd-catalyzed cascade alkoxycarbonylative macrolactonization to construct THP/THF-containing bridged macrolactones in one step from alkendiols is described. Products with various ring sizes and substituents were obtained. Challenging macrolactones involving tertiary alcohols were synthesized...

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Bibliografski detalji
Glavni autori: Bai, Yu, Davis, Dexter C., Dai, Mingji
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126560/
https://ncbi.nlm.nih.gov/pubmed/24825410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201403006
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