Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.

The role of Escherichia coli DNA polymerase (Pol) II in producing or avoiding mutations was investigated by replacing the chromosomal Pol II gene (polB+) by a gene encoding an exonuclease-deficient mutant Pol II (polBex1). The polBex1 allele increased adaptive mutations on an episome in nondividing...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Foster, P L, Gudmundsson, G, Trimarchi, J M, Cai, H, Goodman, M F
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1995
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41264/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7644519/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.17.7951
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