Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.

The role of Escherichia coli DNA polymerase (Pol) II in producing or avoiding mutations was investigated by replacing the chromosomal Pol II gene (polB+) by a gene encoding an exonuclease-deficient mutant Pol II (polBex1). The polBex1 allele increased adaptive mutations on an episome in nondividing...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Foster, P L, Gudmundsson, G, Trimarchi, J M, Cai, H, Goodman, M F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1995
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC41264/
https://ncbi.nlm.nih.gov/pubmed/7644519
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