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Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.

The role of Escherichia coli DNA polymerase (Pol) II in producing or avoiding mutations was investigated by replacing the chromosomal Pol II gene (polB+) by a gene encoding an exonuclease-deficient mutant Pol II (polBex1). The polBex1 allele increased adaptive mutations on an episome in nondividing...

詳細記述

保存先:
書誌詳細
主要な著者: Foster, P L, Gudmundsson, G, Trimarchi, J M, Cai, H, Goodman, M F
フォーマット: Artigo
言語:Inglês
出版事項: 1995
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC41264/
https://ncbi.nlm.nih.gov/pubmed/7644519
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