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Phosphoproteome Dynamics in Onset and Maintenance of Oncogene-induced Senescence
Expression of the BRAF(V600E) oncoprotein is known to cause benign lesions, such as melanocytic nevi (moles). Despite the oncogenic function of mutant BRAF, these lesions are arrested by a cell-autonomous mechanism called oncogene-induced senescence. Infrequently, nevi can progress to malignant mela...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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The American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125739/ https://ncbi.nlm.nih.gov/pubmed/24961811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.035436 |
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