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Phosphoproteome Dynamics in Onset and Maintenance of Oncogene-induced Senescence
Expression of the BRAF(V600E) oncoprotein is known to cause benign lesions, such as melanocytic nevi (moles). Despite the oncogenic function of mutant BRAF, these lesions are arrested by a cell-autonomous mechanism called oncogene-induced senescence. Infrequently, nevi can progress to malignant mela...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Biochemistry and Molecular Biology
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125739/ https://ncbi.nlm.nih.gov/pubmed/24961811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.035436 |
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