Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice

Runx2 and Axin2 regulate skeletal development. We recently determined that Axin2 and Runx2 molecularly interact in differentiating osteoblasts to regulate intramembranous bone formation, but the relationship between these factors in endochondral bone formation was unresolved. To address this, we exa...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: McGee-Lawrence, Meghan E., Carpio, Lomeli R., Bradley, Elizabeth W., Dudakovic, Amel, Lian, Jane B., van Wijnen, Andre J., Kakar, Sanjeev, Hsu, Wei, Westendorf, Jennifer J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125446/
https://ncbi.nlm.nih.gov/pubmed/24973690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.06.022
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi