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Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice
Runx2 and Axin2 regulate skeletal development. We recently determined that Axin2 and Runx2 molecularly interact in differentiating osteoblasts to regulate intramembranous bone formation, but the relationship between these factors in endochondral bone formation was unresolved. To address this, we exa...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125446/ https://ncbi.nlm.nih.gov/pubmed/24973690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.06.022 |
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