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Runx2 is required for early stages of endochondral bone formation but delays final stages of bone repair in Axin2-deficient mice

Runx2 and Axin2 regulate skeletal development. We recently determined that Axin2 and Runx2 molecularly interact in differentiating osteoblasts to regulate intramembranous bone formation, but the relationship between these factors in endochondral bone formation was unresolved. To address this, we exa...

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Detalhes bibliográficos
Main Authors: McGee-Lawrence, Meghan E., Carpio, Lomeli R., Bradley, Elizabeth W., Dudakovic, Amel, Lian, Jane B., van Wijnen, Andre J., Kakar, Sanjeev, Hsu, Wei, Westendorf, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125446/
https://ncbi.nlm.nih.gov/pubmed/24973690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2014.06.022
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