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Sclerostin Deficient Mice Rapidly Heal Bone Defects by Activating β-Catenin and Increasing Intramembranous Ossification
We investigated the influence of the osteocyte protein, sclerostin, on fracture healing by examining the dynamics and mechanisms of repair of single-cortex, stabilized femoral defects in sclerostin knockout (Sost(−/−); KO) and sclerostin wild-type (Sost(+/+); WT) mice. Fourteen days following genera...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3876417/ https://ncbi.nlm.nih.gov/pubmed/24211207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.10.155 |
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