White matter hyperintensities and cerebral amyloidosis: Necessary and sufficient for clinical expression of Alzheimer’s disease?

CONTEXT: Current hypothetical models emphasize the importance of beta amyloid in Alzheimer’s disease (AD) pathogenesis, although amyloid alone is not sufficient to account for the dementia syndrome. The impact of small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH)...

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Autori principali: Provenzano, Frank A., Muraskin, Jordan, Tosto, Giuseppe, Narkhede, Atul, Wasserman, Ben T., Griffith, Erica Y., Guzman, Vanessa A., Meier, Irene B., Zimmerman, Molly E., Brickman, Adam M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124641/
https://ncbi.nlm.nih.gov/pubmed/23420027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2013.1321
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