Reconsidering harbingers of dementia: Progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence

Accumulating evidence implicates small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH) on T2-weighted MRI, in the pathogenesis and diagnosis of Alzheimer's disease (AD). Cross-sectional volumetric measures of WMH, particularly in the parietal lobes, are associa...

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Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Brickman, Adam M., Zahodne, Laura B., Guzman, Vanessa A., Narkhede, Atul, Meier, Irene B., Griffith, Erica Y., Provenzano, Frank A., Schupf, Nicole, Manly, Jennifer J., Stern, Yaakov, Luchsinger, José A., Mayeux, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268124/
https://ncbi.nlm.nih.gov/pubmed/25155654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.07.019
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