Reconsidering harbingers of dementia: Progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence

Accumulating evidence implicates small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMH) on T2-weighted MRI, in the pathogenesis and diagnosis of Alzheimer's disease (AD). Cross-sectional volumetric measures of WMH, particularly in the parietal lobes, are associa...

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Bibliographic Details
Published in:Neurobiol Aging
Main Authors: Brickman, Adam M., Zahodne, Laura B., Guzman, Vanessa A., Narkhede, Atul, Meier, Irene B., Griffith, Erica Y., Provenzano, Frank A., Schupf, Nicole, Manly, Jennifer J., Stern, Yaakov, Luchsinger, José A., Mayeux, Richard
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268124/
https://ncbi.nlm.nih.gov/pubmed/25155654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.07.019
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