Safety Studies on Intravenous Administration of Oncolytic Recombinant Vesicular Stomatitis Virus in Purpose-Bred Beagle Dogs

VSV-IFNβ-NIS is a novel recombinant oncolytic vesicular stomatitis virus (VSV) with documented efficacy and safety in preclinical murine models of cancer. To facilitate clinical translation of this promising oncolytic therapy in patients with disseminated cancer, we are utilizing a comparative oncol...

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Autors principals: LeBlanc, Amy K., Naik, Shruthi, Galyon, Gina D., Jenks, Nathan, Steele, Mike, Peng, Kah-Whye, Federspiel, Mark J., Donnell, Robert, Russell, Stephen J.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
Matèries:
Pre-Clinical Safety Trials
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124537/
https://ncbi.nlm.nih.gov/pubmed/24219832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2013.165
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