Safety Studies on Intravenous Administration of Oncolytic Recombinant Vesicular Stomatitis Virus in Purpose-Bred Beagle Dogs

VSV-IFNβ-NIS is a novel recombinant oncolytic vesicular stomatitis virus (VSV) with documented efficacy and safety in preclinical murine models of cancer. To facilitate clinical translation of this promising oncolytic therapy in patients with disseminated cancer, we are utilizing a comparative oncol...

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Detalles Bibliográficos
Autores principales: LeBlanc, Amy K., Naik, Shruthi, Galyon, Gina D., Jenks, Nathan, Steele, Mike, Peng, Kah-Whye, Federspiel, Mark J., Donnell, Robert, Russell, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2013
Materias:
Pre-Clinical Safety Trials
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124537/
https://ncbi.nlm.nih.gov/pubmed/24219832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/humc.2013.165
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