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Chloride sensing by WNK1 kinase involves inhibition of autophosphorylation
WNK1 [with no lysine (K)] is a serine-threonine kinase associated with a form of familial hypertension. WNK1 is at the top of a kinase cascade leading to phosphorylation of several cotransporters, in particular those transporting sodium, potassium, and chloride (NKCC), sodium and chloride (NCC), and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123527/ https://ncbi.nlm.nih.gov/pubmed/24803536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005050 |
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