Precisely Ordered Phosphorylation Reactions in the p38 Mitogen-activated Protein (MAP) Kinase Cascade

The MAP kinase cascades, composed of a MAP3K, a MAP2K, and a MAPK, control switch responses to extracellular stimuli and stress in eukaryotes. The most important feature of these modules is thought to be the two double phosphorylation reactions catalyzed by MAP3Ks and MAP2Ks. We addressed whether th...

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Detalhes bibliográficos
Main Authors: Humphreys, John M., Piala, Alexander T., Akella, Radha, He, Haixia, Goldsmith, Elizabeth J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743502/
https://ncbi.nlm.nih.gov/pubmed/23744074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.462101
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