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p38 MAP Kinase and MAPKAP Kinases MK2/3 Cooperatively Phosphorylate Epithelial Keratins

The MAPK-activated protein kinases (MAPKAP kinases) MK2 and MK3 are directly activated via p38 MAPK phosphorylation, stabilize p38 by complex formation, and contribute to the stress response. The list of substrates of MK2/3 is increasing steadily. We applied a phosphoproteomics approach to compare p...

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Détails bibliographiques
Auteurs principaux: Menon, Manoj B., Schwermann, Jessica, Singh, Anurag Kumar, Franz-Wachtel, Mirita, Pabst, Oliver, Seidler, Ursula, Omary, M. Bishr, Kotlyarov, Alexey, Gaestel, Matthias
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963412/
https://ncbi.nlm.nih.gov/pubmed/20724476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132357
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