MAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cells

The structurally related MAPK-activated protein kinases (MAPKAPKs or MKs) MK2, MK3 and MK5 are involved in multiple cellular functions, including cell-cycle control and cellular differentiation. Here, we show that after deregulation of cell-cycle progression, haematopoietic stem cells (HSCs) in MK2-...

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Huvudupphovsmän: Schwermann, Jessica, Rathinam, Chozhavendan, Schubert, Maria, Schumacher, Stefanie, Noyan, Fatih, Koseki, Haruhiko, Kotlyarov, Alexey, Klein, Christoph, Gaestel, Matthias
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688528/
https://ncbi.nlm.nih.gov/pubmed/19369945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.100
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