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Upregulation of RGS4 and downregulation of CPI-17 mediate inhibition of colonic muscle contraction by interleukin-1β
The pro-inflammatory cytokine IL-1β contributes to the reduced contractile responses of gut smooth muscle observed in both animal colitis models and human inflammatory bowel diseases. However, the mechanisms are not well understood. The effects of IL-1β on the signaling targets mediating acetylcholi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123227/ https://ncbi.nlm.nih.gov/pubmed/17959727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00300.2007 |
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