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G(i)-coupled receptors mediate phosphorylation of CPI-17 and MLC(20) via preferential activation of the PI3K/ILK pathway

Sustained smooth-muscle contraction or its experimental counterpart, Ca(2+) sensitization, by G(q/13)-coupled receptor agonists is mediated via RhoA-dependent inhibition of MLC (myosin light chain) phosphatase and MLC(20) (20 kDa regulatory light chain of myosin II) phosphorylation by a Ca(2+)-indep...

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Detalhes bibliográficos
Main Authors: Huang, Jiean, Mahavadi, Sunila, Sriwai, Wimolpak, Hu, Wenhui, Murthy, Karnam S.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1450000/
https://ncbi.nlm.nih.gov/pubmed/16472257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051772
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