MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells

BACKGROUND: Regulator of G-protein Signaling 4 (RGS4) plays an important role in regulating smooth muscle contraction, cardiac development, neural plasticity and psychiatric disorder. However, the underlying regulatory mechanisms remain elusive. Our recent studies have shown that upregulation of Rgs...

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Detalhes bibliográficos
Main Authors: Zhang, Yonggang, Li, Fang, Liu, Shu, Wang, Hong, Mahavadi, Sunila, Murthy, Karnam S., Khalili, Kamel, Hu, Wenhui
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335800/
https://ncbi.nlm.nih.gov/pubmed/22545125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035646
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