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MEKK1-MKK4-JNK-AP1 Pathway Negatively Regulates Rgs4 Expression in Colonic Smooth Muscle Cells

BACKGROUND: Regulator of G-protein Signaling 4 (RGS4) plays an important role in regulating smooth muscle contraction, cardiac development, neural plasticity and psychiatric disorder. However, the underlying regulatory mechanisms remain elusive. Our recent studies have shown that upregulation of Rgs...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yonggang, Li, Fang, Liu, Shu, Wang, Hong, Mahavadi, Sunila, Murthy, Karnam S., Khalili, Kamel, Hu, Wenhui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335800/
https://ncbi.nlm.nih.gov/pubmed/22545125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035646
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