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Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, affecting 1–3% of the population over 65. Mutations in the ubiquitin E3 ligase parkin are the most common cause of autosomal recessive PD. The parkin protein possesses potent cell-protective properties and has bee...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4123072/ https://ncbi.nlm.nih.gov/pubmed/24991765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.278 |
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