Supraspinal gene transfer by intrathecal adeno-associated virus serotype 5

We report the pattern of transgene expression across brain regions after intrathecal delivery of adeno-associated virus serotype 5 (AAV5). Labeling in hindbrain appeared to be primarily neuronal, and was detected in sensory nuclei of medulla, pontine nuclei, and all layers of cerebellar cortex. Expr...

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Autori principali: Schuster, Daniel J., Belur, Lalitha R., Riedl, Maureen S., Schnell, Stephen A., Podetz-Pedersen, Kelly M., Kitto, Kelley F., McIvor, R. Scott, Vulchanova, Lucy, Fairbanks, Carolyn A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122912/
https://ncbi.nlm.nih.gov/pubmed/25147505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2014.00066
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