Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture

BACKGROUND: Neuronal transduction by adeno-associated viral (AAV) vectors has been demonstrated in cortex, brainstem, cerebellum, and sensory ganglia. Intrathecal delivery of AAV serotypes that transduce neurons in dorsal root ganglia (DRG) and spinal cord offers substantial opportunities to 1) furt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Vulchanova, Lucy, Schuster, Daniel J, Belur, Lalitha R, Riedl, Maureen S, Podetz-Pedersen, Kelly M, Kitto, Kelley F, Wilcox, George L, McIvor, R Scott, Fairbanks, Carolyn A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900238/
https://ncbi.nlm.nih.gov/pubmed/20509925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-31
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