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IgG in cervicovaginal mucus traps HSV and prevents vaginal Herpes infections

IgG is the predominant immunoglobulin in cervicovaginal mucus (CVM), yet how IgG in mucus can protect against infections is not fully understood. IgG diffuses rapidly through cervical mucus, slowed only slightly by transient adhesive interactions with mucins. We hypothesize this almost unhindered di...

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Detalhes bibliográficos
Main Authors: Wang, Ying-Ying, Kannan, Arthi, Nunn, Kenetta L., Murphy, Michael A., Subramani, Durai B., Moench, Thomas, Cone, Richard, Lai, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4122653/
https://ncbi.nlm.nih.gov/pubmed/24496316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2013.120
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