Herpes simplex virus binding IgG traps HSV in human cervicovaginal mucus across the menstrual cycle and diverse vaginal microbial composition

IgG possesses an important yet little recognized effector function in mucus: IgG bound to viral surface can immobilize otherwise readily diffusive viruses to the mucin matrix, excluding them from contacting target cells and facilitating their elimination by natural mucus clearance mechanisms. Cervic...

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Detalhes bibliográficos
Publicado no:Mucosal Immunol
Main Authors: Schroeder, Holly A., Nunn, Kenetta L., Schaefer, Alison, Henry, Christine E., Lam, Felix, Pauly, Michael H., Whaley, Kevin J., Zeitlin, Larry, Humphrys, Mike S., Ravel, Jacques, Lai, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485947/
https://ncbi.nlm.nih.gov/pubmed/29988116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0054-z
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