Herpes simplex virus binding IgG traps HSV in human cervicovaginal mucus across the menstrual cycle and diverse vaginal microbial composition

IgG possesses an important yet little recognized effector function in mucus: IgG bound to viral surface can immobilize otherwise readily diffusive viruses to the mucin matrix, excluding them from contacting target cells and facilitating their elimination by natural mucus clearance mechanisms. Cervic...

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Foilsithe in:Mucosal Immunol
Main Authors: Schroeder, Holly A., Nunn, Kenetta L., Schaefer, Alison, Henry, Christine E., Lam, Felix, Pauly, Michael H., Whaley, Kevin J., Zeitlin, Larry, Humphrys, Mike S., Ravel, Jacques, Lai, Samuel K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485947/
https://ncbi.nlm.nih.gov/pubmed/29988116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0054-z
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