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Structural effects of PrP polymorphisms on intra- and interspecies prion transmission

Understanding the molecular parameters governing prion propagation is crucial for controlling these lethal, proteinaceous, and infectious neurodegenerative diseases. To explore the effects of prion protein (PrP) sequence and structural variations on intra- and interspecies transmission, we integrate...

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書誌詳細
主要な著者: Angers, Rachel, Christiansen, Jeffrey, Nalls, Amy V., Kang, Hae-Eun, Hunter, Nora, Hoover, Edward, Mathiason, Candace K., Sheetz, Michael, Telling, Glenn C.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121815/
https://ncbi.nlm.nih.gov/pubmed/25034251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404739111
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