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Structural effects of PrP polymorphisms on intra- and interspecies prion transmission
Understanding the molecular parameters governing prion propagation is crucial for controlling these lethal, proteinaceous, and infectious neurodegenerative diseases. To explore the effects of prion protein (PrP) sequence and structural variations on intra- and interspecies transmission, we integrate...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121815/ https://ncbi.nlm.nih.gov/pubmed/25034251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1404739111 |
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