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Structural plasticity of 4-α-helical bundles exemplified by the puzzle-like molecular assembly of the Rop protein

The dimeric Repressor of Primer (Rop) protein, a widely used model system for the study of coiled-coil 4-α-helical bundles, is characterized by a remarkable structural plasticity. Loop region mutations lead to a wide range of topologies, folding states, and altered physicochemical properties. A prot...

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Detalhes bibliográficos
Main Authors: Amprazi, Maria, Kotsifaki, Dina, Providaki, Mary, Kapetaniou, Evangelia G., Fellas, Georgios, Kyriazidis, Ioannis, Pérez, Javier, Kokkinidis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121800/
https://ncbi.nlm.nih.gov/pubmed/25024213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322065111
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