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Structural plasticity of 4-α-helical bundles exemplified by the puzzle-like molecular assembly of the Rop protein
The dimeric Repressor of Primer (Rop) protein, a widely used model system for the study of coiled-coil 4-α-helical bundles, is characterized by a remarkable structural plasticity. Loop region mutations lead to a wide range of topologies, folding states, and altered physicochemical properties. A prot...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121800/ https://ncbi.nlm.nih.gov/pubmed/25024213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322065111 |
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