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Expression, purification and crystallization of a protein resulting from the inversion of the amino-acid sequence of a helical bundle

Earlier studies have found that the occurrence of inverse sequence identity in proteins is not indicative of three-dimensional similarity, but rather leads to different folds or unfolded proteins. Short helices, however, frequently keep their conformations when their sequences are inverted. To explo...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Kefala, Aikaterini, Kotsifaki, Dina, Providaki, Mary, Amprazi, Maria, Kokkinidis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5287371/
https://ncbi.nlm.nih.gov/pubmed/28045394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16020173
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