Targeted Next Generation Sequencing Identifies Clinically Actionable Mutations in Patients with Melanoma

Somatic sequencing of cancers has produced new insight into tumorigenesis, tumor heterogeneity, and disease progression, but the vast majority of genetic events identified are of indeterminate clinical significance. Here we describe a NextGen sequencing approach to fully analyze 248 genes, including...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jeck, William R., Parker, Joel, Carson, Craig C., Shields, Janiel M., Sambade, Maria J., Peters, Eldon C., Burd, Christin E., Thomas, Nancy E., Chiang, Derek Y., Liu, Wenjin, Eberhard, David A., Ollila, David, Grilley-Olson, Juneko, Moschos, Stergios, Hayes, D. Neil, Sharpless, Norman E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121659/
https://ncbi.nlm.nih.gov/pubmed/24628946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12238
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