APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability

Development of higher rates of nondiabetic glomerulosclerosis (GS) in African Americans has been attributed to two coding sequence variants (G1 and G2) in the APOL1 gene. To date, the cellular function and the role of APOL1 variants (Vs) in GS are still unknown. In this study, we examined the effect...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Lan, Xiqian, Jhaveri, Aakash, Cheng, Kang, Wen, Hongxiu, Saleem, Moin A., Mathieson, Peter W., Mikulak, Joanna, Aviram, Sharon, Malhotra, Ashwani, Skorecki, Karl, Singhal, Pravin C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121568/
https://ncbi.nlm.nih.gov/pubmed/24899058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00647.2013
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars