Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1-AS expression

Although large numbers of long noncoding RNAs (lncRNAs) expressed in the mammalian nervous system have been detected, their functions and mechanisms of regulation remain to be fully clarified. It has been reported that the lncRNA antisense transcript for β-secretase-1 (BACE1-AS) is elevated in Alzhe...

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Main Authors: LIU, TE, HUANG, YONGYI, CHEN, JIULIN, CHI, HUIYING, YU, ZHIHUA, WANG, JIAN, CHEN, CHUAN
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121421/
https://ncbi.nlm.nih.gov/pubmed/24970022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2014.2351
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