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Sensitive and Continuous Screening of Inhibitors of β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) at Single SPR Chips

Developments of new methods that meet the demand of high-throughput, high-fidelity screening of hit compounds are important to searching modalities of important diseases such as neurological disorders, HIV, and cancer. A surface plasmon resonance (SPR)-based method capable of continuously screening...

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Detalhes bibliográficos
Main Authors: Yi, Xinyao, Hao, Yuanqiang, Ning, Xia, Wang, Jianxiu, Quintero, Monica, Li, Ding, Zhou, Feimeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635668/
https://ncbi.nlm.nih.gov/pubmed/23432118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac303624z
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