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Inhibition of Cdk2 kinase activity selectively targets the CD44(+)/CD24(−/Low) stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells

Inflammatory breast cancer (IBC) is an angioinvasive and most aggressive type of advanced breast cancer characterized by rapid proliferation, chemoresistance, early metastatic development and poor prognosis. IBC tumors display a triple-negative breast cancer (TNBC) phenotype characterized by centros...

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Detaylı Bibliyografya
Asıl Yazarlar: OPYRCHAL, MATEUSZ, SALISBURY, JEFFREY L., IANKOV, IANKO, GOETZ, MATHEW P., McCUBREY, JAMES, GAMBINO, MARIO W., MALATINO, LORENZO, PUCCIA, GIUSEPPE, INGLE, JAMES N., GALANIS, EVANTHIA, D’ASSORO, ANTONINO B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: D.A. Spandidos 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121417/
https://ncbi.nlm.nih.gov/pubmed/24970653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2523
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