Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells

Although the majority of breast cancers initially respond to the cytotoxic effects of chemotherapeutic agents, most breast cancer patients experience tumor relapse and ultimately die because of drug resistance. Breast cancer cells undergoing epithelial to mesenchymal transition (EMT) acquire a CD44(...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Opyrchal, Mateusz, Gil, Malgorzata, Salisbury, Jeffrey L., Goetz, Mathew P., Suman, Vera, Degnim, Amy, McCubrey, James, Haddad, Tufia, Iankov, Ianko, Kurokawa, Chenye B., Shumacher, Nicole, Ingle, James N., Galanis, Evanthia, D’Assoro, Antonino B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5710966/
https://ncbi.nlm.nih.gov/pubmed/29207686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20610
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