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Inhibition of Rho associated coiled-coil forming kinase increases efficacy of measles virus infection in vitro and in vivo
RhoA and its downstream effector, Rho associated coiled-coil forming kinase (ROCK) are known regulators of formation of actin cytoskeleton in cells. Actin cytoskeleton is involved in paramyxovirus infection. We examined the effect of ROCK inhibition on MV cytopathic effect and replication. Treatment...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903406/ https://ncbi.nlm.nih.gov/pubmed/24157925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.58 |
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