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Inhibition of Rho associated coiled-coil forming kinase increases efficacy of measles virus infection in vitro and in vivo
RhoA and its downstream effector, Rho associated coiled-coil forming kinase (ROCK) are known regulators of formation of actin cytoskeleton in cells. Actin cytoskeleton is involved in paramyxovirus infection. We examined the effect of ROCK inhibition on MV cytopathic effect and replication. Treatment...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903406/ https://ncbi.nlm.nih.gov/pubmed/24157925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.58 |
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