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Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age

Alterations in DNA methylation have been proposed to create a field cancerization state in the colon, where molecular alterations that predispose cells to transformation occur in histologically normal tissue. However, our understanding of the role of DNA methylation in field cancerization is limited...

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Sonraí Bibleagrafaíochta
Main Authors: Kaz, Andrew M, Wong, Chao-Jen, Dzieciatkowski, Slavomir, Luo, Yanxin, Schoen, Robert E, Grady, William M
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121360/
https://ncbi.nlm.nih.gov/pubmed/24413027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27650
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