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Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age
Alterations in DNA methylation have been proposed to create a field cancerization state in the colon, where molecular alterations that predispose cells to transformation occur in histologically normal tissue. However, our understanding of the role of DNA methylation in field cancerization is limited...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4121360/ https://ncbi.nlm.nih.gov/pubmed/24413027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27650 |
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