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Patterns of DNA methylation in the normal colon vary by anatomical location, gender, and age

Alterations in DNA methylation have been proposed to create a field cancerization state in the colon, where molecular alterations that predispose cells to transformation occur in histologically normal tissue. However, our understanding of the role of DNA methylation in field cancerization is limited...

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Detalhes bibliográficos
Main Authors: Kaz, Andrew M, Wong, Chao-Jen, Dzieciatkowski, Slavomir, Luo, Yanxin, Schoen, Robert E, Grady, William M
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121360/
https://ncbi.nlm.nih.gov/pubmed/24413027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.27650
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