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HIV-Derived ssRNA Binds to TLR8 to Induce Inflammation-Driven Macrophage Foam Cell Formation

Even though combined anti-retroviral therapy (cART) dramatically improves patient survival, they remain at a higher risk of being afflicted with non-infectious complications such as cardiovascular disease (CVD). This increased risk is linked to persistent inflammation and chronic immune activation....

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Autors principals: Bernard, Mark A., Han, Xinbing, Inderbitzin, Sonya, Agbim, Ifunanya, Zhao, Hui, Koziel, Henry, Tachado, Souvenir D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121254/
https://ncbi.nlm.nih.gov/pubmed/25090652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104039
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