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A Quantitative Microscopy Technique for Determining the Number of Specific Proteins in Cellular Compartments

This protocol describes a method to determine both the average number and variance of proteins in the few to tens of copies in isolated cellular compartments, such as organelles and protein complexes. Other currently available protein quantification techniques either provide an average number but la...

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Detalhes bibliográficos
Main Authors: Mutch, Sarah A., Gadd, Jennifer C., Fujimoto, Bryant S., Kensel-Hammes, Patricia, Schiro, Perry G., Bajjalieh, Sandra M., Chiu, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4121127/
https://ncbi.nlm.nih.gov/pubmed/22094731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.414
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