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Stereoselective Formation of Trisubstituted Vinyl Boronate Esters by the Acid-Mediated Elimination of α-Hydroxyboronate Esters

[Image: see text] The copper-catalyzed diboration of ketones followed by an acid-catalyzed elimination leads to the formation of 1,1-disubstituted and trisubstituted vinyl boronate esters with moderate to good yields and selectivity. Addition of tosic acid to the crude diboration products provides t...

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Detalhes bibliográficos
Main Authors: Guan, Weiye, Michael, Alicia K., McIntosh, Melissa L., Koren-Selfridge, Liza, Scott, John P., Clark, Timothy B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120978/
https://ncbi.nlm.nih.gov/pubmed/24915498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo500773t
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